Clinical signs of equine asthma, formerly known as COPD or RAO, occur when a genetically susceptible horse inhales an allergen to which they are allergic.

This results in airway spasm and an increased production of mucus and inflammatory cells within the airway resulting in a cough, increased respiratory rate and effort and decreased performance to name but a few. The severity of clinical signs vary from mild to severe.

Dust is commonly implicated, but some horses present during the summer months when pollen levels are high.

Diagnosis is frequently based on compatible clinical signs but can be confirmed through airway endoscopy and laboratory analysis of airway fluid samples.

In the past, treatment of asthma relied heavily on bronchodilators and steroids in addition to environmental modifications.

Recently, nebulised alpha-2-macroglobulins has shown promise in the treatment of asthma cases and equine vet Leona has treated a number of our own patients in addition to referral patients using this product.

Alpha-2-macroglobulins are a natural anti-inflammatory molecule which can be harvested from a patient’s own blood, meaning it is a benign and natural product.

In addition to its use in the treatment of joint disease, it can also be nebulised to treat inflammation associated with equine asthma.

Suitable candidates for treatment include those patients where steroids need to be avoided, patients who have not responded to conventional treatment methods or competition horses who require maintenance therapy.

In summary, a really exciting addition to our toolbox for treating equine asthma!

For more information and to see if your horse could benefit from alpha-2-macroglobulins as a treatment for asthma call 01772 861300 to speak to Leona.